The impact of viral infection on the immune system , according to researchers , may help to explain why some people develop autoimmune diseases - potentially dangerous processes of the body's own tissues .
The theory of the potential link between viral infection and autoimmune diseases is long . Is presented as an opportunity for the first time in conducting observational study , which draws attention to the fact that patients with systemic lupus erythematosus ( SLE ) have elevated levels of antibodies.
The most significant evidence comes from the established link between the virus and the development of multiple sclerosis (MS) and SLE - positive test results were observed in 99% of patients.
However, this fact only shows that the development of the studied pathologies often preceded by infection. This process should include other factors that researchers from around the world in a systematic , hoping to unravel the complex epidemiological , molecular puzzle .Australian scientist Michael P. Pender University of Queensland also published his hypothesis that chronic autoimmune diseases are caused by infectious lymphocytes after infection.
Most professionals who are interested in this hypothesis believe that this relationship is based on the principles of molecular mimicry in which the structure of the central nervous system or DNA recognized by the immune system as components of EBV, cause damage to organs and systems.However , Dr Pender believes that molecular mimicry may cause not any virus or bacteria.
When the immune system recognizes the number of new threats , its response can be excessive and contribute to the development of autoimmune pathology. Autoreactive cells are capable of synthesizing potentially pathogenic antibodies, which then fall into the various organs and can lead to the synthesis of specific antibodies.
In most cases it is asymptomatic or manifest mild clinical symptoms. Experts point out that most serious reactions observed during infection in adolescence. Consequently infection during adolescence may cause a cascade of autoimmune responses .
Scientists note that the studies included in the meta-analysis with a degree of heterogeneity , and therefore the results should be interpreted with caution. However, they believe that the hypothesis that infection with EBV plays an important role in the development of autoimmune diseases is firmly established.
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