It is known that mental depression is a disorder with a complex mechanism of formation . One of the main risk factors associated with its development are stressful events and genetic predisposition.
In many scientific sources often discussed issue is the connecting link between stress and depression . Only a few of those who have experienced stress , then developed a depressive disorder . However, until recently been poorly understood genetic factors that influence susceptibility to stress.
The new systematic review of a group of scientists from the UK, led by Dr. Georgina Hosand assessed the effect of the polymorphism of the gene encoding a neurotrophic factor for stressful events .
The main function of this protein in the body is to support neuronal survival , the growth and formation of new synapses . Increase its activity observed in depressed patients undergoing psychotherapy or pharmacotherapy , not only to improve memory and learning , but also reduces the symptoms of this disease.
Variations of BDNF gene also resulted in vulnerability to stress . For a more detailed study of this question , the researchers analyzed the results of relevant studies published up to the end of last year. Examined in detail 22 studies involving a total participation of 14,233 volunteers in them.Generally, meta-analysis has shown that there is a significant correlation between the stressful events or variations of BDNF gene on persons with depression .
The results obtained according to scientists suggest that there are some individuals ' genetic vulnerability to the negative experience. "
The authors of the study also indicated that the BDNF gene may contain an impressive number of polymorphisms , which may also be involved in the formation of a depression in adverse environmental conditions .
0 коментара:
Публикуване на коментар